This paper aggregates validation status of the NPF/CNI framework. It distinguishes protocol validation (FEN, CDF, auto‑reject) from weight‑structure validation (simulation‑only, 77% confidence), states limitations upfront, and provides implementation guidance for researchers, policymakers, and AI safety. A forward‑looking research agenda outlines next steps: field trials, cross‑cultural calibration, neuroimaging, and intervention studies.